The greatest danger from extreme weather is in highly populated, poor regions of the world, the report warns, but no corner of the globe - from Mumbai to Miami - is immune. The document by a Nobel Prize-winning panel of climate scientists forecasts stronger tropical cyclones and more frequent heat waves, deluges and droughts.
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The 594-page report blames the scale of recent and future disasters on a combination of man-made climate change, population shifts and poverty.
This report by the panel is the first to look at the less common but far more noticeable extreme weather changes, which recently have been costing on average about $US80 billion ($A76.75 billion) a year in damage.
"We mostly experience weather and climate through the extreme," said Stanford University climate scientist Chris Field, who is one of the report's top editors. "That's where we have the losses. That's where we have the insurance payments. That's where things have the potential to fall apart.
"There are lots of places that are already marginal for one reason or another," Field said. But it's not just poor areas: "There is disaster risk almost everywhere."
The scientists say that some places, particularly parts of Mumbai in India, could become uninhabitable from floods, storms and rising seas. In 2005, over 24 hours nearly one metre of rain fell on the city, killing more than 1000 people and causing massive damage. Roughly 2.7 million people live in areas at risk of flooding.
Other cities at lesser risk include Miami, Shanghai, Bangkok, China's Guangzhou, Vietnam's Ho Chi Minh City, Burma's Rangoon and India's Kolkata. The people of small island nations, such as the Maldives, may also need to abandon their homes because of rising seas and fierce storms.
"The decision about whether or not to move is achingly difficult and I think it's one that the world community will have to face with increasing frequency in the future," Field said in a telephone news conference.
The study says forecasts that some tropical cyclones - which includes hurricanes in the United States - will be stronger because of global warming, but the number of storms should not increase and may drop slightly.
Some other specific changes in severe weather that the scientists said they had the most confidence in predicting include more heatwaves and record hot temperatures worldwide, increased downpours in Alaska, Canada, northern and central Europe, East Africa and north Asia.